CCLR research has focused on:
in vitro and in vivo biochemical studies characterizing the tear film and measuring the impact of contact lens materials on the eye;
the rate at which instilled drops dissipate from the ocular surface;
the impact of eye-drop viscosity on the length of time a solution remains on the ocular surface and its impact on the volume of tears in the lower tear meniscus;
the impact of rewetting agents on in-eye comfort and on protein deposition associated with silicone hydrogel contact lenses;
the use of optical coherence tomography in the quantification of tears, including pre-corneal tear film thickness, tear meniscus height and volume;
quantifying mucomimetic components in tears in patients that commonly report dry eye symptoms, including soft contact lens wearers, post-menopausal women and Sjögrens patients;
investigating the sensation of dryness and discomfort, using novel technology designed to take continuous measurements of subjective symptoms;
characterizing the sensory components of ocular discomfort using novel scaling techniques and questionnaires.